How to control ants? Ants Or Termites how do we tell the difference? Ants in homes are a common problem. Despite thorough housekeeping, ants can be persistent. Pest control treatment plans would include eliminating the entire colony, which is the only way to eradicate ants. Spraying household pesticides will only kill a few at best. Any small opening, is enough for ants to gain access into your premises. They are constantly in search of either sweet based food, protein/grease based foods, water based or dry based food. Once they find a food source, ants leave a pheromone trail for other ants to follow. Do I have Ants or Termites?